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2000•Journal of Heze Medical CollegeRequires access

The Effects of Enalapril and Captopril on Hemodynamics after Acute Myocardial Infarction in Rats

Jian Tian

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Abstract

Objective To investigate the mechanism of the left vetricular remodeling after acute myocardial infarction,we examined the effects of 3 weeks treatment with angiotesin converting enzyme inhibitors,Enalapril and Captopril,on hemodynamics in mycardial-infarcted rats.Methods The rats were divided into four groups:SO,sham-operated;MI; MI Enalapril treated.and MI Captopril treated. Results The LVEDP were increased significantly after MI ,after using Enalapril and Captopril, LVEDP were decreased significantly(P0.01), Enalapril and Captopril had no difference(P0.01).Conclusion The use of Enalapril and Captopril after MI may improve the cardiac function, Enalapril and Captopril have no difference.

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What this paper is about

Objective To investigate the mechanism of the left vetricular remodeling after acute myocardial infarction,we examined the effects of 3 weeks treatment with angiotesin converting enzyme inhibitors,Enalapril and Captopril,on hemodynamics in mycardial-infarcted rats.Methods The rats were divided into four groups:SO,sham-operated;MI; MI Enalapril treated.and MI Captopril treated. Results The LVEDP were increased significantly after MI ,after using Enalapril and Captopril, LVEDP were decreased significantly(P0.01), Enalapril and Captopril had no difference(P0.01).Conclusion The use of Enalapril and Captopril after MI may improve the cardiac function, Enalapril and Captopril have no difference.

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Available abstract

Objective To investigate the mechanism of the left vetricular remodeling after acute myocardial infarction,we examined the effects of 3 weeks treatment with angiotesin converting enzyme inhibitors,Enalapril and Captopril,on hemodynamics in mycardial-infarcted rats.Methods The rats were divided into four groups:SO,sham-operated;MI; MI Enalapril treated.and MI Captopril treated. Results The LVEDP were increased significantly after MI ,after using Enalapril and Captopril, LVEDP were decreased significantly(P0.01), Enalapril and Captopril had no difference(P0.01).Conclusion The use of Enalapril and Captopril after MI may improve the cardiac function, Enalapril and Captopril have no difference.

Key concepts: Captopril, Enalapril, Medicine, Preload, Myocardial infarction, Hemodynamics, Cardiology, Internal medicine

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The Effects of Enalapril and Captopril on Hemodynamics after Acute Myocardial Infarction in Rats — Research Paper | ScholarLens