2013•Unpublished venueRequires access

Effects on platelet aggregation of Xinmaikang Capsules in rabbits

Li Fei

Abstract

Objective To investigate the effects on platelet aggregation of Xinmaikang Capsules in rabbits induced by adenosine diphosphate,arachidonic acid and platelet-activating factor.Methods The rate of platelet aggregation was determined by Born method.Results Compared with control group,high dose group of Xinmaikang Capsules(2 g·kg-1) can significantly inhibit platelet aggregation induced by adenosine diphosphate,arachidonic acid and platelet-activating factor(P0.01).Medium dose group of Xinmaikang Capsules(1 g·kg-1) can significantly inhibit platelet aggregation induced by adenosine diphosphate and platelet-activating factor(P0.01).Conlusion Xinmaikang Capsules can inhibit platelet aggregation of rabbits.

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Key concepts: Arachidonic acid, Platelet, Adenosine diphosphate, Platelet aggregation, Chemistry, Adenosine, Platelet-activating factor, Pharmacology