Comparison of effects of transcranial Doppler sonography and transcranial color Doppler ultrasonography on diagnosis of Moyamoya disease with that of DSA

Objectives To summarize the experiences in diagnosing Moyamoya disease by transcranial color Doppler ultrasonography (TCCD) and to evaluate the clinical value of TCCD to noninvasive diagnosis of Moyamoya disease.Methods Of 137 patients with Moyamoa disease diagnosed as by DSA,24 received transcranial Doppler (TCD) examination and 113 did TCCD.The outcomes of TCD and TCCD examination were compared to that DSA which was performed in all the patients.Results The diagnosis of Moyamoya disease was definitely made by TCD in 22,Moyamoya disease was highly suspected in 1 and Moyamoya disease was not detected in 1 of the 24 patients with Moyamoya disease receiving TCD.The positive detected rate of Moyamoya disease by TCD was 95.8%.The diagnosis of Moyamoya disease was definitely made by TCCD in 102,Moyamoya disease was highly suspected in 8 and TCCD examination failed of success in 3 because there were not bone windows through which the sound passed.Conclusions The vessels in the brain bases and changes in their hemodynamics can dynamically be observed in real time by TCD and TCCD.TCCD is more helpful to estimating the occlusion and light stenosis of the intracranial vessels and it is of higher value to diagnosing Moyamoya disease than TCD because it is more sensitive to the blood flow in the stenosed vessels.TCD and TCCD,which are noninvasive methods,should be firstly selected for diagnosing and following up in the patients with Moyamoya disease.