Clinical Effect of Sequential Dialysis Combined with BiPAP on Patients with End-stage Renal Disease Complicated with Acute Left Heart Failure

Objective: To observe the effect of sequential dialysis( SD) combined with Bi PAP on patients with end- stage renal disease( ESRD) complicated with acute left heart failure. Methods: 60 cases of ESRD patients complicated with acute left heart failure were enrolled in this study. All the patients were divided into: SD combined with Bi PAP observation group( n = 30) and CRRT control group( n = 30). The renal function indexes,blood gas analysis index and clinical effect were compared between the two groups. Results: After treatment,the BUN,Scr,K+,Ca2 +,and P3-was decreased in the two groups( P 0. 05 and P 0. 01).There was no significant difference of above index decreases between the two groups( P 0. 05). After treatment,Pa O2 and Pa CO2 was improved in the two groups( P 0. 05). However,the changes was better in observation group than that in control group( P 0. 05). The dialysis time in control group was( 64. 32 ± 12. 96) h,which was significantly higher than that of( 51. 36 ± 7. 92) h in observation group( P 0. 05). The clinical effective rate was 96. 7%( 29 /30) in observation group and 93. 3%( 28 /30) in control group. There was no significant difference between the two groups( P 0. 05). The expense was( 9274. 5 ± 814. 6) yuan in control group,which was higher than that of( 7 116. 2 ± 658. 4) yuan in observation group( P 0. 01). Conclusion: The clinical effect of SD combined with Bi PAP in the treatment of ESRD complicated with acute left heart failure had no significant difference with CRRT treatment. But the combined therapy was better in treating patients with hypoxia,and greatly reduce the cost.