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2011•Unpublished venueRequires access

Application of Ultrafiltration Membrane in Production of Vitamin B_(12)

Tao Chen

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Abstract

Mycelium, protein and other impurities in non-pretreated broth of Vitamin B_(12)were removed by Ultra-flo UF system.Filter broth of Vitamin B_(12) was filtered with MWCO of 10 million of Ultra-flo membrane, filtrate quality was higher,average membrane flux can reach 122.52 L / m~(-2)·h~(-1),flux decay is slower.After washing, contaminated membrane has no significant difference with the new film.Ultra-flo UF system has strong processing capability with a long and stable operation.The ultrafiltration system has successful applicated in the North China Pharmaceutical Group Corporation.

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What this paper is about

Mycelium, protein and other impurities in non-pretreated broth of Vitamin B_(12)were removed by Ultra-flo UF system.Filter broth of Vitamin B_(12) was filtered with MWCO of 10 million of Ultra-flo membrane, filtrate quality was higher,average membrane flux can reach 122.52 L / m~(-2)·h~(-1),flux decay is slower.After washing, contaminated membrane has no significant difference with the new film.Ultra-flo UF system has strong processing capability with a long and stable operation.The ultrafiltration system has successful applicated in the North China Pharmaceutical Group Corporation.

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Available abstract

Mycelium, protein and other impurities in non-pretreated broth of Vitamin B_(12)were removed by Ultra-flo UF system.Filter broth of Vitamin B_(12) was filtered with MWCO of 10 million of Ultra-flo membrane, filtrate quality was higher,average membrane flux can reach 122.52 L / m~(-2)·h~(-1),flux decay is slower.After washing, contaminated membrane has no significant difference with the new film.Ultra-flo UF system has strong processing capability with a long and stable operation.The ultrafiltration system has successful applicated in the North China Pharmaceutical Group Corporation.

Key concepts: Ultrafiltration (renal), Membrane, Chromatography, Chemistry, Membrane filter, Vitamin, Membrane technology, Food science

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