Correlation between carotid intima-media thickness and pulse wave velocity and ankle brachial index

Objective:To perspectively study the relationship of carotid intima-media thickness between pulse wave velocity and ankle brachial index. Method:In 115 cases (61 females),carotid intima-media thickness (IMT) were measured with ultrasound. Brachial-ankle artery pulse wave (baPWV) and ankle-arm blood pressure index (ABI) were measured with Japan's Kolin Arteriosclerosis Insturment. At the same time,serum TC,TG,HDL,LDL,fasting blood glucose (FBG),serum uric acid (UA),body mass index ( BMI) were mensurated.The mean comparison,t test,simple correlation analysis,multiple linear regression analysis (enter method and stepwise method) were used. Result:The average of carotid IMTs of 115 subjects were 0.64±0.11 mm,Carotid IMT of male was significantly higher than female,Carotid IMT of equal or greater than 50-year-old group was significantly higher than group of less than 50 years old,Carotid IMT of systolic blood pressure equal or greater than 140mmHg group was significantly higher than group of systolic blood pressure less than 140 mmHg,Carotid IMT of group with hypertension was significantly higher than without hypertension. Carotid IMT related to age,baPWV,SBP and ABI,the correlation coefficient was 0.625,0.460,0.412 and 0.361 respectively. Multiple regression analysis showed that age and SBP are independent factors of Carotid IMT. Conclusion:Carotid IMT,baPWV and ABI are positively correlated. We can select one of them for early detecting blood vessels diseases according to the respective conditions.