Detection of the diagnosis about pancreatic cancer with the 3 tumor markers in serum

Objective To establish a analysis method about pancreatic cancer with the 3 tumor markers of the TSGF、CA242 and CA19-9 in serum. Methods To assay the content of TSGF, CA242 and CA19-9 about the normal 200, the pancreatitis 60,the malignant lymphoma 41 and the pancreatic cancer 85 with Colorimetry of Biochemistry and ELISA. Results It′s in a ratio of about true positive percent to false positive percent, was named likelihood ratio. The results display that TSGF, CA242 and CA19-9 their positive likelihood ratio priority are 5.4, 12.7 and 6.6, the negative likelihood ratio priority are 0.10, 0.19 and 0.15. the highest sensitivity and specificity of TSGF are 91.8% and 93.5%.TSGF is close to CA19-9 at the availability. In combined test, all of them positive and changed to 77.6%,100% and 100%. The level of TSGF and CA242 in head of pancreas cancer are extra highest in the part of all pancreas, body of pancreas and head of pancreas,but CA19-9 hasn′t to do with part of the pancreas. Conclusion It′s to elevate their sensitivity and specificity in combination with TSGF, CA242 and CA19-9 to diagnose about pancreatic cancer .Their expressions what important function an act of diagnosing the pancreatic cancer.