Effects of the Treatment with Continuous Positive Airway Pressure for One Night on the Sleep Architecture of the Patients with Obstructive Sleep Apnea Syndrome

Objective To investigate the effects of the treatment with continuous positive airway pressure(CPAP) for one night on sleep architecture of the patients with obstructive sleep apnea syndrome(OSAS).Methods 113 patients with slight,moderate or serious OSAS diagnosed by polysomnogram(PSG)were treated by CPAP for at least 7 hours during one night.In the mean time,PSG was used to monitor the changes of sleep of the patients and some parameters related to the severity of the disease.Results After treatment with CPAP for one night,the ratio of the patients′ sleep durations at stage 1 and stage 2 to tota1 sleep time(TST)decreased significantly(P0.05),4.5% and 10.1% respectively.And the ratio of the deep sleep time(stage 3 and stage 4)to total sleep time increased by 6.5%(P0.05).The ratio of the time of rapid eye movement(REM) sleep to TST increased by 8%(P0.05).Apnea hyponea index(AHI) decreased by 59.6%(P0.05).Minimum SaO2 and average SaO2 increased by 18.0% and 5% respectively(P0.05).Conclusion CPAP treatment for one night can significantly improve the sleep architecture of OSAS patients,increasing the duration of deep sleep,decreasing AHI and increasing SaO2.