Studies on Quality Standard of Dingxin Pills

OBJECTIVE To establish the quality standard for Dingxin pills.METHODSTLC was applied to identify Radix Glycyrrhizae,Radix Angelica Sinensis and Radix Polygalae Willd in this prescription, and baicalin content in Radix Scutellariae was determined by HPLC. A C18 column(250 mm×4.6 mm,5 μm) was used with the mobile phase of acetonitrile-0.2%phosphoric acid (22∶78) at the detection wavelength of 280 nm. RESULTSRadix Glycyrrhizae,Radix Angelica Sinensis and Radix Polygalae could be identified by TLC.The baicalin linear rang of 0.193 4-1.160 6 μg, and the average recovery was 101.45%(RSD=1.2%,n=6). CONCLUSIONThe evaluation methods are simple, sensitive, accurate and reproducible, and can be used for the quality control of this medicine.