Distribution of 578 patients with positive detection of syphilis

Objective To analyze the distribution of patients with positive detection of syphilis and syphilis susceptible populations, and then provide basis for prevention and treatment of syphilis. Methods Clinical data(including age, sex, type of treatment and department) about 578 treponema pallidum particle assay(TPPA) positive cases who underwent combined detection of TPPA and ring card test of plasma regain(RPR) in our hospital in 2013 were analyzed and then RPR titers distribution of patients who showed double positive after combined detection was analyzed. Results Of the 578 TPPA positive patients, 295 cases were male(51.0%) and 283 cases were female(49.0%), and there was no statistically significant difference of gender(P0.05). 490 cases were outpatient(84.8%) and 88 cases were inpatient(15.2%), and it showed statistically significant difference(P0.05). The age range of 578 TPPA positive patients was 21 to 40 years old, and the highest positive rate of serologic reaction was in 20 years old or less group(92.6%), the difference showed statistical significance comparing with other age groups. The department of 578 TPPA positive patients was mainly distributed in the outpatient of dermatology, and 437 cases(coincidence rate, 75.6%) showed double positive detected by combined detection. The distribution of RPR titer was 1∶1 to 1∶128, and the number of patients decreased with the increase of titers. Conclusion According to the analysis of the susceptible population, syphilis infection mainly exists in young and middle-aged patients, some are children or elder. The patients are mainly distributed in the outpatient, especially in the dermatology department. The distribution of positive cases concentrates in patients with low titer. Prevention knowledge education about syphilis should be strengthened and timely and effective tracking detection should be made in the syphilis crowd, which is of significant importance in control of widespread of syphilis.