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2003•Clinical EndoscopyRequires access

A Case of Adenocarcinoma Arising in Hyperplastic Polyp in the Stomach

Soojin Park, Hyun-Gun Kim, Jae-Hoon Yang, Hae-Jung Song, So‐Young Jin, Chang-Beom Ryu, Jin-Oh Kim, Jooyoung Cho, Joon-Seong Lee, Moon-Sung Lee, Chan-Sup Shim

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Abstract

Epithelial gastric polyps can be categorized as hyperplastic or adenomatous polyps. Hyperplastic polyps are predominant, comprising 75 to 90% of gastric polyps. It has been generally accepted that adenomatous gastric polyps exhibit malignant change. However, potential of malignant transformation of hyperplastic gastric polyps was originally denied and have been rarely reported, the incidence varying from 1.5 to 2.1%. The size and the associated dysplasia of polyps seem to be important in transformation to gastric carcinoma. Most of the reported cases of hyperplastic gastric polyps with transformation to adenocarcinoma were histopathologically well differentiated. We report a rare case of moderately differentiated adenocarcinoma arising in a hyperplastic polyp on the greater curvature of the midbody in the stomach with a brief review of the literatures.

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What this paper is about

Epithelial gastric polyps can be categorized as hyperplastic or adenomatous polyps. Hyperplastic polyps are predominant, comprising 75 to 90% of gastric polyps. It has been generally accepted that adenomatous gastric polyps exhibit malignant change. However, potential of malignant transformation of hyperplastic gastric polyps was originally denied and have been rarely reported, the incidence varying from 1.5 to 2.1%. The size and the associated dysplasia of polyps seem to be important in transformation to gastric carcinoma. Most of the reported cases of hyperplastic gastric polyps with transformation to adenocarcinoma were histopathologically well differentiated. We report a rare case of moderately differentiated adenocarcinoma arising in a hyperplastic polyp on the greater curvature of the midbody in the stomach with a brief review of the literatures.

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Available abstract

Epithelial gastric polyps can be categorized as hyperplastic or adenomatous polyps. Hyperplastic polyps are predominant, comprising 75 to 90% of gastric polyps. It has been generally accepted that adenomatous gastric polyps exhibit malignant change. However, potential of malignant transformation of hyperplastic gastric polyps was originally denied and have been rarely reported, the incidence varying from 1.5 to 2.1%. The size and the associated dysplasia of polyps seem to be important in transformation to gastric carcinoma. Most of the reported cases of hyperplastic gastric polyps with transformation to adenocarcinoma were histopathologically well differentiated. We report a rare case of moderately differentiated adenocarcinoma arising in a hyperplastic polyp on the greater curvature of the midbody in the stomach with a brief review of the literatures.

Key concepts: Hyperplastic Polyp, Medicine, Gastric Polyp, Malignant transformation, Dysplasia, Adenomatous polyps, Adenocarcinoma, Gastroenterology

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A Case of Adenocarcinoma Arising in Hyperplastic Polyp in the Stomach — Research Paper | ScholarLens