Advances of Phenoxazines: Synthesis, Reactivity and Their Medicinal Applications

Phenoxazines are an important class of heterocycles, which are emerging in the field of medicinal chemistry. They exhibit numerous biological activities, including antiviral, anticancer, anti-Alzheimer, antidiabetic, antioxidant, anti-inflammatory, antibiotic and many more. The present review focuses on the chemistry along with the medicinal applications of the phenoxazine moiety, in order to provide a greater insight for the development of future phenoxazine therapeutics. Keywords: Phenoxazines, actinomycin, phenoxazine synthesis, phenoxazine biosynthesis, phenoxazine applications, phenoxazine bioactivities, phenoxazine natural products.