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2003•Journal of Postgraduates of MedicineRequires access

MEASUREMENT OF PLASMA ENDOTOXIN LEVEL IN PATIENTS WITH ALCOHOLIC LIVER DISEASES

Li Zang

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Abstract

Objective to measure plasma endotoxin in patients with alcoholic liver diseases.Methods The peripheral blood plasma endotoxin level were quantitatively measured in the following four groups of subjects (98 cases), including alcoholic fatty liver,alcoholic hepatitis,alcoholic liver cirrhosis and normal controls by Matrix Chromo-Hao test .Results Endotoxin was detected in 9.00% in the normal controls and in 12.12% of patients with alcoholic fatty liver,55.55% in alcoholic hepatitis and 68.01% in alcoholic liver cirrhosis .Except patients with alcoholic fatty liver, the endotoxin levels in the others were significantly higher than normal controls (P0.01).And the peripheral blood plasma endotoxin levels in the latter two groups was also significantly higher than the nomal controls (P0.01).Conclusion There is a higher incidence of endotoxemia in patients with alcoholic liver diseases.

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Objective to measure plasma endotoxin in patients with alcoholic liver diseases.Methods The peripheral blood plasma endotoxin level were quantitatively measured in the following four groups of subjects (98 cases), including alcoholic fatty liver,alcoholic hepatitis,alcoholic liver cirrhosis and normal controls by Matrix Chromo-Hao test .Results Endotoxin was detected in 9.00% in the normal controls and in 12.12% of patients with alcoholic fatty liver,55.55% in alcoholic hepatitis and 68.01% in alcoholic liver cirrhosis .Except patients with alcoholic fatty liver, the endotoxin levels in the others were significantly higher than normal controls (P0.01).And the peripheral blood plasma endotoxin levels in the latter two groups was also significantly higher than the nomal controls (P0.01).Conclusion There is a higher incidence of endotoxemia in patients with alcoholic liver diseases.

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Available abstract

Objective to measure plasma endotoxin in patients with alcoholic liver diseases.Methods The peripheral blood plasma endotoxin level were quantitatively measured in the following four groups of subjects (98 cases), including alcoholic fatty liver,alcoholic hepatitis,alcoholic liver cirrhosis and normal controls by Matrix Chromo-Hao test .Results Endotoxin was detected in 9.00% in the normal controls and in 12.12% of patients with alcoholic fatty liver,55.55% in alcoholic hepatitis and 68.01% in alcoholic liver cirrhosis .Except patients with alcoholic fatty liver, the endotoxin levels in the others were significantly higher than normal controls (P0.01).And the peripheral blood plasma endotoxin levels in the latter two groups was also significantly higher than the nomal controls (P0.01).Conclusion There is a higher incidence of endotoxemia in patients with alcoholic liver diseases.

Key concepts: Medicine, Alcoholic hepatitis, Alcoholic liver disease, Fatty liver, Alcoholic fatty liver, Internal medicine, Gastroenterology, Cirrhosis

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MEASUREMENT OF PLASMA ENDOTOXIN LEVEL IN PATIENTS WITH ALCOHOLIC LIVER DISEASES — Research Paper | ScholarLens