Clinical study on relationship between syndrome of traditional Chinese medicine and sympathetic skin response in diabetic peripheral neuropathy

Objective To explore the relationship between traditional Chinese medicine(TCM) syndrome and sympathetic skin response(SSR) in patients with diabetic peripheral neuropathy(DPN).Methods 378 patients with DPN were selected to record SSR test results,blood glucose,blood pressure,serum lipids,TCM symptoms and were classified as TCM syndrome Qi-deficiency,Yin-deficiency,Yang-deficiency,blood-stasis,phlegm-dampness and Qi-depression.Results The main syndrome type was Yin and Yang-deficiency combined with blood-stasis.With age and the course progress,the proportion of Yin-deficiency,Qi and Yin-deficiency decreased,and the proportion of Yin and Yang-deficiency increased.The rate of SSR abnormality was 67.5%,and abnormal SSR rate of Yin and Yang-deficiency group was significantly higher than other groups(P0.05).In this group,Yin and Yang-deficiency combined with blood-stasis,Yin and Yang-deficiency combined with blood-stasis and phlegm-dampness were significant positive correlated with SSR abnormality.Conclusion SSR abnormality was related with Yin and Yang-deficiency combined with blood-stasis,Yin and Yang-deficiency combined with blood-stasis and phlegm-dampness,to provide the basis for TCM syndrome in patients with DPN.