Long-term Observation On Massive Allograft Bones Implantation for Defects

Objective: To report the long term observation of large segment allografts in the treatment for bone tumor. Methods: A retrospective analysis of 70 consecutive cases of large segment allograft implantations after resection of bone tumor was conducted. The allogeneic bone healing were observed. Seventy cases had an average age of 38.4 years(ranged 14～71 years). There were 8 osteosarcomas, 45 aggressive giant cell tumor of bone, 17 other bone tumors. The mean length of allograft was 15.5cm(ranged 8～25cm). The types of fixation included common intramedullary nailing in 25 cases, inter locking intramedullary nailing in 21 cases, plate in 2 cases, screw in 22 cases. Results: Following up period ranged from 5 years to 22 years(averaged 10.5 years) in 70 cases. 68 cases had union and 2 non unions. The major complications were recurrence in 8 cases, infection 7 cases, fracture 3 cases, absorption and collapse of articular surface 6 cases. The patients were evaluated in regard to function with use of Mankin system. 23 cases had excellent results,19 cases good, 12 cases fair. Satisfactory rate was 78.2%. Conclusion: The allograft bones implantation is the most desirable graft material for repair of bone defected in course of limb salvage following resections of bone tumor. Satisfactory results can be obtained with the indication controlled.