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Changes of AFP mRNA expression in blood after treatment of percutaneous ethanol injection for hepatocellular carcinoma (HCC)

Guang-Xiang Qian

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Abstract

Objective To study effects of percutaneous ethanol injection (PEI) in the treatment of hepatocellular carcinoma(HCC).2 Methods We detected blood samples from 9 HCC patients by nested RTPCR to find out AFP mRNA after PEI treatment for 35 sessions within 2 weeks. ResultsBZ AFP mRNA was positive in 4 out of 9 HCC patients.Among the 4 patients AFP mRNA turned negative in 3 at the end of PEI therapy. HZConclutions PEI seems to be effective in preventing the hematogenous dissemination of the tumor cells.

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What this paper is about

Objective To study effects of percutaneous ethanol injection (PEI) in the treatment of hepatocellular carcinoma(HCC).2 Methods We detected blood samples from 9 HCC patients by nested RTPCR to find out AFP mRNA after PEI treatment for 35 sessions within 2 weeks. ResultsBZ AFP mRNA was positive in 4 out of 9 HCC patients.Among the 4 patients AFP mRNA turned negative in 3 at the end of PEI therapy. HZConclutions PEI seems to be effective in preventing the hematogenous dissemination of the tumor cells.

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Available abstract

Objective To study effects of percutaneous ethanol injection (PEI) in the treatment of hepatocellular carcinoma(HCC).2 Methods We detected blood samples from 9 HCC patients by nested RTPCR to find out AFP mRNA after PEI treatment for 35 sessions within 2 weeks. ResultsBZ AFP mRNA was positive in 4 out of 9 HCC patients.Among the 4 patients AFP mRNA turned negative in 3 at the end of PEI therapy. HZConclutions PEI seems to be effective in preventing the hematogenous dissemination of the tumor cells.

Key concepts: Hepatocellular carcinoma, Medicine, Percutaneous ethanol injection, Messenger RNA, Percutaneous, Internal medicine, Gastroenterology, Carcinoma

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