The trend in research of carbapenem antibiotics

Carbapenem is a new group of β-lactam antibiotics with a broad antibacterial spectrum and a different structure from traditional β-l actam antibiotics.Carbapenem is active against gram-positive,gram-negative,aer obic,and anaerobic bacteria and is stable to lactamases.It can be divided into type 1 carbapenem:unstable to DHP-I;type 2 carbapenem:stable to DHP-I but cann ot be used alone;and type 3 carbapenem:stable to DHP-I and can be used alone.