Clinical efficacy of TKRP surgery and its effect on serum PSA level for treating the patients with benign prostatic hyperplasia

Objective To investigate the clinical efficacy and safety of transurethral plasmakinetic resection of prostate(TKRP) in patients with benign prostatic hyperplasia(BPH),and the impact on patients' serum prostate specific antigen(PSA) levels.Methods A total of 336 cases of patients with BPH were divided into TKRP group and transurethral resection of the prostate(TURP) group according to the surgical approach.The operation time,blood loss,weight of resection of prostate and hospitalization time of the two groups were observed.The patients were followed up for 3 months,the IPSS score,QOL score,postoperative Qmax and postoperative complications of the two groups were observed.Before surgery and 1 month after surgery the serum PSA levels of two groups were detected.Results The operation time,blood loss and hospitalization time of TKRP group were significantly lower than TURP group,the weight of resection of prostate was significantly higher than the TURP group,compared to both the significant difference(P 0.01).The postoperative IPSS and QOL scores of TKRP group were significantly lower than TURP group,the postoperative Qmax was significantly higher than the TURP group,compared to both the significant difference(P 0.01).There were no complications in the TKRP group.Compared with the preoperative PAS level,the postoperative PAS levels of the two groups reduced significantly(P 0.01),and the PAS level of TKRP group was lower than the TURP group,compared the difference was significant(P 0.01).Conclusion The TKRP has a shorter operative time,less bleeding,patients recover quickly and no postoperative complications.It can significantly improve the quality of life of patients and inhibit the release of the PSA.The TKRP is a safe and effective surgical method for treating the BPH.