Characteristics and Clinical Significance of T Lymphocyte Subsets in Newfound HIV/AIDS Patients

Objective To detect T lymphocyte subsets in newfound HIV/AIDS patients and find out immunological status of HIV/AIDS patients.Methods The subjects were the newfound 115 patients with HIV infection/AIDS from 2009 to 2011,and retrospective analysis was done in the consequence of T lymphocyte subsets detection,including the absolute number of CD3+CD4+ lymphocytes,CD3+CD8+lymphocytes and ratio of CD3+CD4+/CD3+CD8+.Results The mean value of absolute number of T lymphocyte:CD3+CD4+T lymphocyte was(229±215)/μL,CD3+CD8+T lymphocyte was(919±756)/μL,ratio of CD3+CD4+/CD3+CD8+was 0.27±0.21.There were 87(75.7%)patients,whose CD4+T lymphocyte was 350/μL,62(53.9%)patients' CD4+ T lymphocyte was 200/μL,33(28.7%)patients' CD4+ T lymphocyte was 200/μL.The T lymphocyte subsets of patients with different gender and age had no distinct difference.Conclusion The consequence of T lymphocyte subsets detection could reflect the immune deficiency and severity of the disease,and has important clinical significance for seleting suitable intervention measure.