Regulatory effects of insulin and glucose on aquaporin adipose expression in 3T3-L1 adipocytes
Chen Jia-we
Abstract
Chen Jia-we
Abstract
Aquaporin adipose (AQPap) is the physiological glycerol channel specific to adipocytes. By means of semiquantitive RT-PCR and Western blotting, this study showed that insulin was a negative regulator of AQPap expression, while high concentration of glucose could increase AQPap expression.
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Aquaporin adipose (AQPap) is the physiological glycerol channel specific to adipocytes. By means of semiquantitive RT-PCR and Western blotting, this study showed that insulin was a negative regulator of AQPap expression, while high concentration of glucose could increase AQPap expression.
Key concepts: Internal medicine, Endocrinology, Adipose tissue, 3T3-L1, Aquaporin, Regulator, Insulin, Blot