2005•Chinese Journal of Cardiovascular MedicineRequires access
Plasma levels of atrial natriuretic peptide and brain natriuretic peptide in patients with acute myocardial infarction in Killip classesII underwent percutaneous coronary intervention
Y Wang
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Abstract
Objective To determine the plasma levels of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) change in patients with acute myocardial infarction (AMI) in Killip classesⅡ underwent percutaneous coronary intervention (PCI). Methods 40 consecutive patients with AMI in Killip classesⅡ were studied prospectively, other 40 patients with AMI in Killip classesⅡact as control. Blood samples were withdrawn at AMI 48 hours, 24 hours after PCI and 1 month after PCI. Soluble ANP and BNP levels were assayed at presentation. Results The levels of ANP and BNP of trial group were similar to control group at AMI 48 hour, but that decreased after PCI in trial patients. Only the levels of ANP and BNP at 1 month after PCI were significantly lower than AMI 48 hour(P0.05). In control group there were no difference at that times. Conclusion The levels of ANP and BNP in patients with AMI in Killip classesⅡwere significantly decreased after PCI.