Clinical evaluation of Kangfute for bacterial vaginosis

Objective ① To observe the effect of Kangfute for bacterial vaginosis (BV).② To explore the vaginal flora of BV.Methods A multicenter, prospective, case control, random clinical study was conducted, in which Kangfute was used in 54 cases with BV as study group, and metronidazole in 52 cases as control group.Symptoms, signs, examination of laboratory and curative effect were compared between the two groups.Results ① Increased vaginal discharge and odorous discharge were complained by more than eighty percent of patients with BV.Yellowish vaginal discharge (60.4%), the diamine test positive (80.0%), pH4.5 (100%), the clue cells (100%) were presented.② The efficiency of Kangfute and metronidazole were 92.0% and 86.0% respectively (P0.05) after 1 week of treatment, 100.0% and 92.5% (P=0.002) after 4 weeks.③ Escherichia coli, Streptococcus heamolyticus, Enterococcus faecalis, Corynebacteriaceae, Streptococcus aglactiae and Staphylococcus epidermidis were the most common bacteria isolated. Conclusions BV needs further investigation, and Kangfute is more effective than metronidazole for bacterial vaginosis.