Application of peritoneal dialysis in the treatment of acute kidney injury

Objective To evaluate the therapeutic effect of peritoneal dialysis(PD) for acute kidney injury (AKI).Methods Clinical data from 42 AKI patients undergoing PD were retrospectively analyzed.Their blood urea nitrogen(BUN),creatinine(Cr),potassium ion([K~+]) and carbon dioxide combining power(CO_2 CP) before and after PD were compared.Results Twenty-nine patients recovered(70.73%),one patient remained on PD treatment(2.38%), one patient discharged without recovery(2.38%),and 11 patients died(26.19%).After PD treatment renal function recovered in 2～38 days,[K~+]declined to normal level in 1～2 days,and CO_2CP returned to normal level in 2～4 days. BUN and SCr lowered by 30.99%and 53.29%,respectively,within 3～4 days,and by 33.92%and 57.36%,respectively, within 5～7 days.Acute tubular necrosis individual severity score(ATNISS) was remarkably higher in died patients than in recovered patients.Conclusion PD has better therapeutic effects for AKI patients,and is the best choice for pediatric AKI.The prognosis of AKI patients mainly depends on the primary disease,the number of failed organs,and the level of ATNISS score.