The cnilical study of interventional treatment in malignant biliary obstruction

Objective To explore the techniques of interventional therapy for malignant biliary obstruction and the teatment after operation . Methods Percutaneous stent implantation and internal - external catheter drainage were adopted in 26 patients (21 males and 5 females ) with malignant biliary obstruction, the age ranged from 35 to 80 years and the mean age was 64 years . Biliary obstruction was caused by panccreatic carcinoma (n=11 ), biliary duct cancer ( n = 9), hepatic carcinoma (n=1 ), metastases (n = 3 ) or carcinoma of gallbladder (n = 2) .Twenty-one patients received biliary stent implantation and internal -external catheter drainage , two patients were simply treated with external catheter drainage , three patients were simply treated with internal - external catheter drainage . Results All catheter drainage were efficient , 21 stents obtained satisfactory internal draining function , no stent replacement in those cases . The serum total bilirubin decreased from 427. 6± 113. 4μmol / L before the procedure to 178. 8 ± 65. 3μmol / L one week after the operation . Subsidence of jaundice was satisfactory in 19 cases , and disappeared unsatisfactory in 2 cases . One case died from the bleeding of bile - ducts at first week after operation . Other cases were followed up for one month , one case died from infection of bile - ducts , and two cases died from failure of more organ among them. Conclusions Percutaneous transhepatic biliary drainage and stent implantation are simple, safe and effective for the malignant biliary obstruction .