ScholarLens Back to search
2011•Acta Scientiarum Naturalium Universitatis SunyatseniRequires access

HPLC Fingerprint of Qutanzhike Granule

Wenyan Zheng, Xiaodong Wang, Wei Peng, Shen Yi, Weiwei Su

Open publisher page 0 citations

Abstract

HPLC fingerprint of Qutanzhike Granule was established with Elite Hypersil BDS column(4.6 mm×250 mm,5 μm),methanol(A) and 0.15% acetic acid(B) as mobile phase.The elution profile was: 0~95 min 15% to 75% A in B(linear gradient).The column temperature was set at 25 ℃ and the flow rate was 1.0 mL/min.The detective wavelength was at 260 nm.19 common peaks were selected as the fingerprint peaks from 12 batches of the production.In the established fingerprint,10 flavonoids were identified by the HPLC-ESI/MS/MS based on MS spetra and standard reference.The method can be used for quality control of Qutanzhike Granule with great precision,accuracy and good reproducibility.

About this research paper

What this paper is about

HPLC fingerprint of Qutanzhike Granule was established with Elite Hypersil BDS column(4.6 mm×250 mm,5 μm),methanol(A) and 0.15% acetic acid(B) as mobile phase.The elution profile was: 0~95 min 15% to 75% A in B(linear gradient).The column temperature was set at 25 ℃ and the flow rate was 1.0 mL/min.The detective wavelength was at 260 nm.19 common peaks were selected as the fingerprint peaks from 12 batches of the production.In the established fingerprint,10 flavonoids were identified by the HPLC-ESI/MS/MS based on MS spetra and standard reference.The method can be used for quality control of Qutanzhike Granule with great precision,accuracy and good reproducibility.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

HPLC fingerprint of Qutanzhike Granule was established with Elite Hypersil BDS column(4.6 mm×250 mm,5 μm),methanol(A) and 0.15% acetic acid(B) as mobile phase.The elution profile was: 0~95 min 15% to 75% A in B(linear gradient).The column temperature was set at 25 ℃ and the flow rate was 1.0 mL/min.The detective wavelength was at 260 nm.19 common peaks were selected as the fingerprint peaks from 12 batches of the production.In the established fingerprint,10 flavonoids were identified by the HPLC-ESI/MS/MS based on MS spetra and standard reference.The method can be used for quality control of Qutanzhike Granule with great precision,accuracy and good reproducibility.

Key concepts: Chromatography, Reproducibility, Granule (geology), High-performance liquid chromatography, Chemistry, Fingerprint (computing), Analytical Chemistry (journal), Acetic acid

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
HPLC Fingerprint of Qutanzhike Granule — Research Paper | ScholarLens