2004•Journal of Qilu OncologyRequires access

Clinical significance of determination of thymidine phosphorylase in therapy evaluation of capecitabine for colorectal cancer

Guo Qiong-xing

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Abstract

The expressive levels of thymidine phosphorylase in colorectal cancer tissues among patients who administrated capecitabine and did not administrated capecitabine were examined by ELISA technicque for evaluating the efficacy of capecitabing. The expressive levels of thymidine phophorylase in colorectal cancer tissues among the patients who administrated capecitabing were higher by 2.59 folds than those among the patients who did not administrated capecibine.In conclusion,the expression levels of thymidine phosphoryseal may be a marker for evaluating efficacy of capecitabine.

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What this paper is about

The expressive levels of thymidine phosphorylase in colorectal cancer tissues among patients who administrated capecitabine and did not administrated capecitabine were examined by ELISA technicque for evaluating the efficacy of capecitabing. The expressive levels of thymidine phophorylase in colorectal cancer tissues among the patients who administrated capecitabing were higher by 2.59 folds than those among the patients who did not administrated capecibine.In conclusion,the expression levels of thymidine phosphoryseal may be a marker for evaluating efficacy of capecitabine.

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Available abstract

The expressive levels of thymidine phosphorylase in colorectal cancer tissues among patients who administrated capecitabine and did not administrated capecitabine were examined by ELISA technicque for evaluating the efficacy of capecitabing. The expressive levels of thymidine phophorylase in colorectal cancer tissues among the patients who administrated capecitabing were higher by 2.59 folds than those among the patients who did not administrated capecibine.In conclusion,the expression levels of thymidine phosphoryseal may be a marker for evaluating efficacy of capecitabine.

Key concepts: Thymidine phosphorylase, Capecitabine, Colorectal cancer, Thymidine, Medicine, Internal medicine, Oncology, Cancer

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