2011•Chinese Journal of Laboratory DiagnosisRequires access

The mRNA results of TGF-β_2 gene between the age-related cataract and the normal lens epithelial cells

Zhang Wen-son

Abstract

Objective To investigate the change of HSP27 and HSP70 expression of lens epithelial cells in age-related cataract.Methods RT-PCR method was used to study mRNA expression levels of TGF-β2 in lens epithelial cells of ARC.Results TGF-β2 mRNA's expression level is higher inARC than in control.Conclusion TGF-β2 is remarkable higher in ARC than in control group which suggests TGF-β2 plays an important role in the development of ARC.

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Key concepts: Messenger RNA, Arc (geometry), Hsp27, Lens (geology), Transforming growth factor, Gene expression, Biology, Hsp70