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STUDY ON THE ANTIFATIGUE EFFECTS OF PROTEIN-BOND POLYSACCHARIDE FROM LENTINUS EDODES

Juan Yang, Moucheng Wu, Shenghua Zhang, Guangyi Liang

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Abstract

Objective: To study the antifatigue effects of protein-bond polysaccharide from Lentinus edodes (Le). Methods: Three doses of protein-bond polysaccharide Le 10 mg/(kg·d),20 mg/(kg·d),50 mg/(kg·d) and 0.9% sodium chloride solution were applied to mice. After seven days, mice were forced to swimming to induce fatigue. Muscle and liver glycogen, serum lactic dehydrogenase(LDH) activity and blood urea nitrogen(BUN) were measured. Results: Administration of protein-bond polysaccharide showed remarkable effects on the reserves of muscle and liver glycogen, serum LDH activity, lowering BUN and clearance rate of BUN before and after exercise. Conclusion: Le has antifatigue effect and its optimum dose is 20 mg/(kg·d).

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What this paper is about

Objective: To study the antifatigue effects of protein-bond polysaccharide from Lentinus edodes (Le). Methods: Three doses of protein-bond polysaccharide Le 10 mg/(kg·d),20 mg/(kg·d),50 mg/(kg·d) and 0.9% sodium chloride solution were applied to mice. After seven days, mice were forced to swimming to induce fatigue. Muscle and liver glycogen, serum lactic dehydrogenase(LDH) activity and blood urea nitrogen(BUN) were measured. Results: Administration of protein-bond polysaccharide showed remarkable effects on the reserves of muscle and liver glycogen, serum LDH activity, lowering BUN and clearance rate of BUN before and after exercise. Conclusion: Le has antifatigue effect and its optimum dose is 20 mg/(kg·d).

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Available abstract

Objective: To study the antifatigue effects of protein-bond polysaccharide from Lentinus edodes (Le). Methods: Three doses of protein-bond polysaccharide Le 10 mg/(kg·d),20 mg/(kg·d),50 mg/(kg·d) and 0.9% sodium chloride solution were applied to mice. After seven days, mice were forced to swimming to induce fatigue. Muscle and liver glycogen, serum lactic dehydrogenase(LDH) activity and blood urea nitrogen(BUN) were measured. Results: Administration of protein-bond polysaccharide showed remarkable effects on the reserves of muscle and liver glycogen, serum LDH activity, lowering BUN and clearance rate of BUN before and after exercise. Conclusion: Le has antifatigue effect and its optimum dose is 20 mg/(kg·d).

Key concepts: Lentinus, Polysaccharide, Glycogen, Chemistry, Blood urea nitrogen, Lactic dehydrogenase, Sodium, Food science

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