2005•Chinese Journal of DisinfectionRequires access

EXPERIMENTAL STUDY ON GERMICIDAL PROPERTIES OF COMPOUND ALDEHYDE ALCOHOL DISINFECTION SOLUTION

NI Xian-sheng

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Abstract

Compound aldehyde alcohol disinfection solution is a liquid preparation composed of the ingredients such as glutaraldehyde and isopropanol.In order to study its germicidal ability,carrier quantitative germicidal test and observation of its disinfection-related properties were carried out.Results: The average killing rate of Bacillus subtilis var.niger spores on carrier exposed to the compound disinfection solution containing glutaraldehyde 20 g/L and 20%~40%(v/v) isopropanol under alkaline condition for 40 min was over 99.9%and attained 100% after exposure for 120 min.The compound disinfection solution showed good germicidal efficacy under alkaline condition and its germicidal efficacy decreased with decreasing pH value.The compound disinfection solution presented low stability,so it should not be stored for long time. Conclusion: The compound aldehyde alcohol disinfection solution has good efficacy in killing spores of Bacillus subtilis var.niger on carrier,but its stability is low.

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What this paper is about

Compound aldehyde alcohol disinfection solution is a liquid preparation composed of the ingredients such as glutaraldehyde and isopropanol.In order to study its germicidal ability,carrier quantitative germicidal test and observation of its disinfection-related properties were carried out.Results: The average killing rate of Bacillus subtilis var.niger spores on carrier exposed to the compound disinfection solution containing glutaraldehyde 20 g/L and 20%~40%(v/v) isopropanol under alkaline condition for 40 min was over 99.9%and attained 100% after exposure for 120 min.The compound disinfection solution showed good germicidal efficacy under alkaline condition and its germicidal efficacy decreased with decreasing pH value.The compound disinfection solution presented low stability,so it should not be stored for long time. Conclusion: The compound aldehyde alcohol disinfection solution has good efficacy in killing spores of Bacillus subtilis var.niger on carrier,but its stability is low.

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Available abstract

Compound aldehyde alcohol disinfection solution is a liquid preparation composed of the ingredients such as glutaraldehyde and isopropanol.In order to study its germicidal ability,carrier quantitative germicidal test and observation of its disinfection-related properties were carried out.Results: The average killing rate of Bacillus subtilis var.niger spores on carrier exposed to the compound disinfection solution containing glutaraldehyde 20 g/L and 20%~40%(v/v) isopropanol under alkaline condition for 40 min was over 99.9%and attained 100% after exposure for 120 min.The compound disinfection solution showed good germicidal efficacy under alkaline condition and its germicidal efficacy decreased with decreasing pH value.The compound disinfection solution presented low stability,so it should not be stored for long time. Conclusion: The compound aldehyde alcohol disinfection solution has good efficacy in killing spores of Bacillus subtilis var.niger on carrier,but its stability is low.

Key concepts: Glutaraldehyde, Bacillus subtilis, Chemistry, Aldehyde, Alcohol, Nuclear chemistry, Spore, Chromatography

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