Clinical study of cerebral palsy in 258 preterm infants.

【Objective】 To investigate the related risk factors、clinical types distributions、the level of movement disorder and neuroimaging characters、the comorbiditie in preterm infants with cerebral palsy(CP).【Methods】 A clinical study of cross section based on Qingdao special hospital.The preterm children with cerebral palsy hospitalized in rehabilitation center from January 2006 to June 2010 were studied.Perinatal data were collected by the researchers using the questionnaire and meeting with children's mother;Gross Motor Function Classification System(GMFCS) was adopted to evaluate the levels of movement disorder;every children accepted the intelligence test,eye examination and speech evaluation.And the children who were suspected with auditory disorders had brain stem auditory evoked potential examination.【Results】 Among the 258 cases,199 cases with spastic type CP.The levels of GMFCS of spastic diplegia and hemiplegia were better than the dyskinetic、spastic tetraplegia and the mixed type(F=4.362,P0.01).The distributions of comorbidites were different between the different types of cerebral palsy and the levels of GMFCS.170 cases(65.89%) with cerebral palsy had periventricular leukomalacia(PVL) which could be seen in all types of CP but more frequently in the spastic diplegia and tetraplegia.These can benefit the early screening and early diagnose of CP of premature and also help the localization and qualitation of the comorbidities.【Conclusions】 CP together with associated disorders become the focus of premature infants.It is important to recognize the clinical aspects,neuroimaging features and the comorbidities of them for etiological research and general rehabilitation administration.