2008•Chinese Journal of PharmaceuticalsRequires access

Application of Eudragit L30D-55 and NE30D to Soft Gel Capsules Enteric Coating

Wang Jian-xin

Open publisher page 0 citations

Abstract

The elongation property of the enteric fi lm of Eudragit L30D-55 could be adjusted with Eudragit NE30D, and its minimum fi lm forming temperature could be decreased with PEG 6000 as plasticizer. The enteric coating formulation of soft gel capsules was optimized by orthogonal design. The qualities of three batches of enteric coating soft gel capsules stored under the condition of (25±2)℃ and RH(60±5)% for 6 months were complied with the enteric specifi cation in ChP 2005.

About this research paper

What this paper is about

The elongation property of the enteric fi lm of Eudragit L30D-55 could be adjusted with Eudragit NE30D, and its minimum fi lm forming temperature could be decreased with PEG 6000 as plasticizer. The enteric coating formulation of soft gel capsules was optimized by orthogonal design. The qualities of three batches of enteric coating soft gel capsules stored under the condition of (25±2)℃ and RH(60±5)% for 6 months were complied with the enteric specifi cation in ChP 2005.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

The elongation property of the enteric fi lm of Eudragit L30D-55 could be adjusted with Eudragit NE30D, and its minimum fi lm forming temperature could be decreased with PEG 6000 as plasticizer. The enteric coating formulation of soft gel capsules was optimized by orthogonal design. The qualities of three batches of enteric coating soft gel capsules stored under the condition of (25±2)℃ and RH(60±5)% for 6 months were complied with the enteric specifi cation in ChP 2005.

Key concepts: Enteric coating, Enteric coated, Plasticizer, Coating, Chemistry, Elongation, PEG ratio, Chromatography

Related papers

Back to paper searchBrowse research topicsOriginal source
Application of Eudragit L30D-55 and NE30D to Soft Gel Capsules Enteric Coating — Research Paper | ScholarLens