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1991•Chinese Journal of Organic ChemistryRequires access

Synthesis,Oxidation-Reduction Potentials and Biological Activity of 1,4-Benzoquinone Derivatives

Gu Lian, Yan Xiao, Xu Jian

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Abstract

1,4-benzoquinone derivatives with a decyl substituent at 6-position,but with different arrangement of substituents(methyl,methoxy,hydrogen,chloro and bromo)on the quinone ring have been synthesized.The structural specificity and oxidation-reduction po-tential of 1,4-'benzoquinones related to the biological functions in mitochondrial succinate-cytochrome C reductase are studied systematically.

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What this paper is about

1,4-benzoquinone derivatives with a decyl substituent at 6-position,but with different arrangement of substituents(methyl,methoxy,hydrogen,chloro and bromo)on the quinone ring have been synthesized.The structural specificity and oxidation-reduction po-tential of 1,4-'benzoquinones related to the biological functions in mitochondrial succinate-cytochrome C reductase are studied systematically.

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Available abstract

1,4-benzoquinone derivatives with a decyl substituent at 6-position,but with different arrangement of substituents(methyl,methoxy,hydrogen,chloro and bromo)on the quinone ring have been synthesized.The structural specificity and oxidation-reduction po-tential of 1,4-'benzoquinones related to the biological functions in mitochondrial succinate-cytochrome C reductase are studied systematically.

Key concepts: Chemistry, Substituent, Quinone, 1,4-Benzoquinone, Ring (chemistry), Benzoquinone, Reductase, Reduction potential

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