ScholarLens Back to search
2015•The Chinese Journal of Modern Applied PharmacyRequires access

Effect of Myricanone on Cell Apoptosis and Cell Cycle in Human Lung Adenocarcinoma A549 Cells

Chen Xua

Open publisher page 0 citations

Abstract

OBJECTIVE To detect the effect of myricanone on cell apoptosis and cell cycle in human lung adenocarcinoma A549 cells. METHODS The early cell apoptosis rate and cell cycle percentage of each group were detected by flow cytomytry. RESULTS Myricanone induced early cell apoptosis of A549 cells in a dose-dependent manner, as well as increased the percentage of A549 cells blocked in G0/G1 stage. CONCLUSION Myricanone could significantly increase the cell apoptosis rate of A549 cells and could block cell cycle of A549 cells in G0/G1 stage.

About this research paper

What this paper is about

OBJECTIVE To detect the effect of myricanone on cell apoptosis and cell cycle in human lung adenocarcinoma A549 cells. METHODS The early cell apoptosis rate and cell cycle percentage of each group were detected by flow cytomytry. RESULTS Myricanone induced early cell apoptosis of A549 cells in a dose-dependent manner, as well as increased the percentage of A549 cells blocked in G0/G1 stage. CONCLUSION Myricanone could significantly increase the cell apoptosis rate of A549 cells and could block cell cycle of A549 cells in G0/G1 stage.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

OBJECTIVE To detect the effect of myricanone on cell apoptosis and cell cycle in human lung adenocarcinoma A549 cells. METHODS The early cell apoptosis rate and cell cycle percentage of each group were detected by flow cytomytry. RESULTS Myricanone induced early cell apoptosis of A549 cells in a dose-dependent manner, as well as increased the percentage of A549 cells blocked in G0/G1 stage. CONCLUSION Myricanone could significantly increase the cell apoptosis rate of A549 cells and could block cell cycle of A549 cells in G0/G1 stage.

Key concepts: A549 cell, Apoptosis, Cell cycle, Cell, Adenocarcinoma, Human lung, Chemistry, Flow cytometry

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Effect of Myricanone on Cell Apoptosis and Cell Cycle in Human Lung Adenocarcinoma A549 Cells — Research Paper | ScholarLens