Clinical analysis in patients with stage I bronchioloalveolar carcinoma and adenocarcinoma

OBJECTIVE:To compare the clinic characteristics and prognostic factors in patients with stage Ⅰ bronchioloalveolar carcinoma (BAC) and adenocarcinoma of the lung. METHODS: Clinic data of 257 inpatient cases with stage Ⅰ BAC and adenocarcinoma in The Cancer Hospital of Tianjin Medical University,were retrospectively reviewed. We made a comparion between the two groups. RESULTS: Stage Ⅰ BAC and adenocarcinoma have apparent differences in gender (P=0.005) and smoking (P=0.015),and they have different imaging characteristics. The 5-year survival rate of Stage Ⅰ BAC (68.0%) was higher than that of adenocarcinoma (46.0%),P=0.0043. The 5-year survival rate of male was higher than female with BAC (P=0.035),while the 5-year survival rate of female was higher than male with adenocarcinoma,P=0.027. The surgical methods have no impact on the 5-year survival rate of Stage Ⅰ BAC, while the surgical methods have apparent impact on the 5-year survival rate of Stage Ⅰ adenocarcinoma, P=0.040. Smoking has no impact on the 5-year survival rate of Stage Ⅰ BAC and adenocarcinoma. CONCLUSIONS: Stage Ⅰ bronchioloalveolar carcinoma is more likely to occure in female. No obvious relation is found with smoking. Lobectomy is performed as standard method in its surgical treatment. The prognosis with BAC is superior to adenocarcinoma,and the prognosis of male is superior to female.