2011•Journal of Jinan UniversityRequires access

New progress on the research studies of microRNA in leukemia

Xiaomao Hu

Abstract

Aim:MicroRNAs(miRNAs) are small,endogenous,nonprotein-coding RNAs of 21~25 nucleotides that play a key role in gene expression control.Extensive miRNA deregulation has been observed in leukemia and miRNA studies indicated its role in the diagnosis and prognosis of leukemia.This review focuses on recent researches on the important roles of microRNAs in leukemia,including acute myeloid leukemia(AML),acute lymphoblastic leukemia(ALL) and chronic lymphocytic leukemia(CLL).

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Available abstract

Key concepts: microRNA, Myeloid leukemia, Leukemia, Chronic lymphocytic leukemia, Cancer research, Biology, Lymphoblastic Leukemia, Gene