Analysis of neonatal congenital hypothyroidism screening and early diagnosis in Weinan area

Objective To summarize and analyze neonatal congenital hypothyroidism(CH)screening and the characteristics of early diagnosis in Weinan area.Methods The neonatal congenital hypothyroidism(CH)screening and diagnosis data in Weinan neonatal disease screening center were analyzed retrospectively from August 2010 to October 2013.Results A total of 71 084 neonates were screened for CH,45 cases of CH were confirmed with an average incidence rate 0.633‰.Pathological jaundice was the major clinical manifestations of children(51.11%),and the children with thyroid stimulating hormone(TSH)≥32mIUL were accounted for 62.22%.After the Pearson correlation analysis,The T4,FT4 levels were positively correlated with the CDCC scores,adaptation IQ and fine motor skill IQ(P0.05).Conclusion The incidence rate of neonatal congenital hypothyroidism in Weinan area is higher,Neonatal disease screening is conducive to the early diagnosis and treatment of these patients,it is worth of improving and popularizing.