Cardiac function improvement after transcatheter closure of atrial septal defect using domestic-made occluder

Objective To evaluate the changes of the cardiac morphology and ventricular function after transcatheter closure of atrial septal defect (ASD) using domestic-made occluder device. Methods 60 patients with secundum-type ASD (27 male, 33 female) had ASD closed with domestic-made occluder device. Echocardiographiy were made at 3 days, 3 months, 6 months and 12 months after the procedure. The ventricular volume was calculated with plane area length method. Results The occipitofrontal and left-right diameter of right atrium and right ventricle decreased significantly 3 days after the procedure (P0.05,P0.01=. Right ventricular end-diastolic volume (RVEDV) reduced significantly (P0.05= and right ventricular ejection fraction (RVEF) had a tendency to normalization. RVEDV and RVEF improved further 3-6 months later. After transcatheter closure, left ventricular end-diastolic and end-systolic volume, left ventricular stroke volume, left ventricular ejection fraction and shortening fraction increased significantly. 12 months after the procedure, cardiac size normalized roughly. Conclusions Transcatheter closure of atrial septal defect with domestic-made occluder device can eliminate the abnormal shunt scussfully, decrease the volume load of the right heart and improve left ventricular systolic function and geometry significantly.