2008•Practical Journal of Medicine & PharmacyRequires access

Clinical observation of radiofrequency catheter ablation for ventricular arrhythmia originating in right ventricular outflow tract

Xiaodong Liu

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Abstract

Objective To observe the clinical effect of radiofrequency catheter ablation (RFCA) for ventricular arrhythmia originating in right ventricular outflow tract (RVOT). Methods RFCA was performed in 48 patients with severely symptomatic ventricular arrhythmia in the RVOT and without response to antiarrhythmic drug. There were 14 men and 34 women aged from 31 to 67 years old (48.4±13.8). No organic heart diseases were found by routine examination; 48 patients were assigned to routine catheter ablation group (n=18) and single catheter ablation group (n=30), their mean frequency of VPS was (16 900.6±7 094.1)/24 hours documented by 24-hour Holter monitoring. Target points were localized by pace mapping. Pace mapping demonstrated identical QRS complex configurations during pacing and during the arrhythmia in at least 11 leads. Results The operation success rates were 88.8% and 90%, respectively. There was no difference between the two groups. The mean number of VPCs was (857.9±2 605.6)/24 hours which was compared with that before ablation their difference had statistical significance(P0.01). The mean number of VPCs was (824.6±2 485.1)/24 hours in routine catheter ablation group and was (877.8±2 605.6)/24 hours in single catheter ablation group (P0.05). One patient in routine catheter ablation group developed aeropleura. There were no late complications in all the patients. Conclusions Catheter ablation of ventricular arrhythmia originating in RVOT is an effective and curative therapy for the patients. Single catheter technique for mapping and ablation of RVOT arrhythmia is effective and safe, meanwhile it can simplify the ablation procedure associated with decreasing expense.

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Objective To observe the clinical effect of radiofrequency catheter ablation (RFCA) for ventricular arrhythmia originating in right ventricular outflow tract (RVOT). Methods RFCA was performed in 48 patients with severely symptomatic ventricular arrhythmia in the RVOT and without response to antiarrhythmic drug. There were 14 men and 34 women aged from 31 to 67 years old (48.4±13.8). No organic heart diseases were found by routine examination; 48 patients were assigned to routine catheter ablation group (n=18) and single catheter ablation group (n=30), their mean frequency of VPS was (16 900.6±7 094.1)/24 hours documented by 24-hour Holter monitoring. Target points were localized by pace mapping. Pace mapping demonstrated identical QRS complex configurations during pacing and during the arrhythmia in at least 11 leads. Results The operation success rates were 88.8% and 90%, respectively. There was no difference between the two groups. The mean number of VPCs was (857.9±2 605.6)/24 hours which was compared with that before ablation their difference had statistical significance(P0.01). The mean number of VPCs was (824.6±2 485.1)/24 hours in routine catheter ablation group and was (877.8±2 605.6)/24 hours in single catheter ablation group (P0.05). One patient in routine catheter ablation group developed aeropleura. There were no late complications in all the patients. Conclusions Catheter ablation of ventricular arrhythmia originating in RVOT is an effective and curative therapy for the patients. Single catheter technique for mapping and ablation of RVOT arrhythmia is effective and safe, meanwhile it can simplify the ablation procedure associated with decreasing expense.

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Available abstract

Objective To observe the clinical effect of radiofrequency catheter ablation (RFCA) for ventricular arrhythmia originating in right ventricular outflow tract (RVOT). Methods RFCA was performed in 48 patients with severely symptomatic ventricular arrhythmia in the RVOT and without response to antiarrhythmic drug. There were 14 men and 34 women aged from 31 to 67 years old (48.4±13.8). No organic heart diseases were found by routine examination; 48 patients were assigned to routine catheter ablation group (n=18) and single catheter ablation group (n=30), their mean frequency of VPS was (16 900.6±7 094.1)/24 hours documented by 24-hour Holter monitoring. Target points were localized by pace mapping. Pace mapping demonstrated identical QRS complex configurations during pacing and during the arrhythmia in at least 11 leads. Results The operation success rates were 88.8% and 90%, respectively. There was no difference between the two groups. The mean number of VPCs was (857.9±2 605.6)/24 hours which was compared with that before ablation their difference had statistical significance(P0.01). The mean number of VPCs was (824.6±2 485.1)/24 hours in routine catheter ablation group and was (877.8±2 605.6)/24 hours in single catheter ablation group (P0.05). One patient in routine catheter ablation group developed aeropleura. There were no late complications in all the patients. Conclusions Catheter ablation of ventricular arrhythmia originating in RVOT is an effective and curative therapy for the patients. Single catheter technique for mapping and ablation of RVOT arrhythmia is effective and safe, meanwhile it can simplify the ablation procedure associated with decreasing expense.

Key concepts: Medicine, Ventricular outflow tract, Ablation, Catheter, Catheter ablation, Cardiology, Radiofrequency catheter ablation, Internal medicine

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