The short-term therapeutic effects of therapy combined radiation with intracavitary solidifying treatment on nasopharyngeal carcinoma

Objective To investigate the therapeutic effects of therapy combined radiation with intracavitary solidifying treatment on nasopharyngeal carcinoma(NPC). Methods Thirty-two cases with NPC were included in this study as treating group and their therapeutic response was compared with that of cases treated simply by radiotherapy.The combined therapy was carried out to the cases with external irradiation given at a dosage of 36 Gy firstly and 50～70 Gy at the total dosage followed after one week of intermittent period,and then,the intracavitary solidifying treatment with microwave diathermy was applied into the tumor focus in the nasopharynx once in the intermittent period and 1 to 4 times after the end of radiotherapy,with the surface temperature of tumor reaching 90±5℃. Results It was shown that the short-term therapeutic effects of this combined therapy was superior to that of simple radiotherapy for the treatment of NPC,with a completely responsive rate of 75%. Conclusions The combined therapy with radiation and intracavitary solidifying procedure of microwave diathermy may be more effective for the treatment of NPC,with a better short-term therapeutic effect on these patients in case of selecting suitable cases and operating in a correct way.