Study on the subtypes of Ureaplasma urealyticum isolated from STD clinic attenders

Objective:We seek to explore the relationship between U.urealyticum subtype 1 and 2 with nongonococcal urethritis. Methods:Urethral samples were collected from patients with and without non-gonococcal urethritis.PCR were performed to subtype U.urealyticum.Serotypes of U.urealyticum were also classified.Results:Of all the samples,24.3%(18/74)were tested positive for subtype 1,59.5%(44/74) were positive for subtype 2,6.8%(5/74) were positive for both subtype 1 and subtype 2.Therefore,subtype 2 was dominant among samples tested.There was no statistically significant difference in percentage of subtype 1 or subtype 2 among patients with or without urethritis.The serotyping result showed that serotype 2,4,7,14 were dominant in both urethritis and non-urethritis group.Conclusion:The result from this study suggests it is unlikely that any specific subtype and serogype of U.urealyticum is related to the development of NGU.Serotypes 2,4,7,14 were dominant strains in the Guangdong region.