2006Acta Academiae Medicinae JiangxiRequires access

Removable Suture Trabeculectomy with Amniotic Membrane Implantation and Mitomycin C for Treatment of Refractory Glaucoma

Lan Xu-da

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Abstract

Objective To explore the efficacy of removable suture trabeculectomy with amniotic membrane implantation and mitomycin C for treatment of refractory glaucoma.Methods Eight patients(10 eyes)with refractory glaucoma underwent removable suture trabeculectomy with amniotic membrane implantation.Trabeculectomy was performed with a limbal-based conjunctival flap using 0.3 mg/mL MMC for 2 min.The IOP,the filtering bleb and the anterior chamber depth were examined at 1 week,1 month and 1 year after surgery respectively.Results There was no shallow anterior chamber happened at week after surgery;One eye showed a postoperative hypotony;The IOP was 23.88 mmHg in 1 eye,7~18 mmHg in 9 eyes.There were 10 eyes that maintained functioning blebs and anterior chamber depth during 1 year follow up period.Conclusion Removable suture trabeculectomy with amniotic membrane implantation and mitomycin C for refractory glaucoma can effectively inhibit the scar formation and reduce the incidence of the complications.

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Objective To explore the efficacy of removable suture trabeculectomy with amniotic membrane implantation and mitomycin C for treatment of refractory glaucoma.Methods Eight patients(10 eyes)with refractory glaucoma underwent removable suture trabeculectomy with amniotic membrane implantation.Trabeculectomy was performed with a limbal-based conjunctival flap using 0.3 mg/mL MMC for 2 min.The IOP,the filtering bleb and the anterior chamber depth were examined at 1 week,1 month and 1 year after surgery respectively.Results There was no shallow anterior chamber happened at week after surgery;One eye showed a postoperative hypotony;The IOP was 23.88 mmHg in 1 eye,7~18 mmHg in 9 eyes.There were 10 eyes that maintained functioning blebs and anterior chamber depth during 1 year follow up period.Conclusion Removable suture trabeculectomy with amniotic membrane implantation and mitomycin C for refractory glaucoma can effectively inhibit the scar formation and reduce the incidence of the complications.

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Available abstract

Objective To explore the efficacy of removable suture trabeculectomy with amniotic membrane implantation and mitomycin C for treatment of refractory glaucoma.Methods Eight patients(10 eyes)with refractory glaucoma underwent removable suture trabeculectomy with amniotic membrane implantation.Trabeculectomy was performed with a limbal-based conjunctival flap using 0.3 mg/mL MMC for 2 min.The IOP,the filtering bleb and the anterior chamber depth were examined at 1 week,1 month and 1 year after surgery respectively.Results There was no shallow anterior chamber happened at week after surgery;One eye showed a postoperative hypotony;The IOP was 23.88 mmHg in 1 eye,7~18 mmHg in 9 eyes.There were 10 eyes that maintained functioning blebs and anterior chamber depth during 1 year follow up period.Conclusion Removable suture trabeculectomy with amniotic membrane implantation and mitomycin C for refractory glaucoma can effectively inhibit the scar formation and reduce the incidence of the complications.

Key concepts: Trabeculectomy, Medicine, Glaucoma, Mitomycin C, Surgery, Bleb (medicine), Fibrous joint, Ophthalmology

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