Advances in research on Bt (Bacillus thuringiensis) receptor proteins in insects

Bacillus thuringienses (Bt) is a widely used bio-insecticide. The Bt receptor protein is very important to the toxicity expression of Bt in insects, and it has been suggested that change of binding ability between this receptor protein and Bt may be the main mechanism of Bt resistance. In this paper, the separation, identification and binding dynamics of the insect Bt receptor protein, and the relationships between Bt toxicity, Bt resistance, receptor proteins, and molecular nature are reviewed.