Application of continuous glucose monitoring system combined with continuous subcutaneous insulin infusion in the treatment of newly diagnosed type 2 diabetes

Objective To observe the glycemic control effect and the islet function recovery of continuous glucose monitoring system(CGMS) combined with continuous subcutaneous insulin infusion(CSII) in the treatment of newly diagnosed type 2 diabetes.Methods A total of 40 cases of newly diagnosed type 2 diabetes were randomly divided into control group and observation group;control group were treated with self-monitoring of blood glucose(SMBG) combined with CSII,and observation group were treated with CGMS combined with CSII.The time for blood glucose reaching the standard,the frequencies of low and high blood sugar,blood sugar fluctuation value,the insulin dosage of a whole day after treatment,and the glucose,insulin,C-peptide levels at different time points before and after treatment were observed.Results All hypoglycemia and hyperglycemia events of CGMS record on the 3rd day of treatment were more than those of SMBG record,but on the 14th day of treatment were the opposite.After intensive treatment for 14 days in two groups,fasting glucose and 2-hour postprandial blood glucose were significantly lower than before treatment(P0.01);2-hour postprandial insulin,C-peptide levels at different time points and Homa-β function index were higher than before treatment(all P0.05),but for the comparation between the two groups,all P0.05.Blood sugar fluctuation and the time for blood glucose reaching the standard in observation group were less than those in control group(all P0.05).Conclusion The combination therapy of CGMS and CSII can make patients with newly diagnosed type 2 diabetes in a shorter period of time achieve more effective,safer and more stable blood sugar control and improve beta-cell function.