2010•Tianran chanwu yanjiu yu kaifaRequires access

Prevention and Therapeutic Effect of Sika Deer Velvet Collagen Hydrolysate on Osteoporosis in Ovariectomized Rats

Xiaobo Qu

Abstract

To evaluate the preventive and therapeutic effects of the collagen extracted from Sika deer velvet(CSDV) on osteoporosis in ovariectomized rats.Histomorphometric indices,biomechanics results and serum biochemical parameters were measured in ovariectomized rats treated with/without CSDV and in sham-operated rats.Compared with the ovariectomized group,CSDV markedly improve bone mineral density(BMD) and bone weight in ovariectomized rats,regulate the ALP and BGP in serum.CSDV was found to play a role in the prevention and treatment of osteoporosis in ovariectomized rats.

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Key concepts: Ovariectomized rat, Osteoporosis, Internal medicine, Endocrinology, Bone mineral, Medicine, Estrogen