Pathological Observation on Spinal Cord of Spinal Cord Injury

Objective: To observe the pathological changes on spinal cord of spinal cord injury and that after dealt with hyperbaric oxygen etc.Methods:SD rats were selected to duplicate SCI model,and HE staining was performed on spinal cord tissues after treated with 0.1MPa HBO and 0.25MPa HBO.Results: In the normal control group,the structure of spinal cord was integrite,the nerve cells eumorphism,iso distribution,cell membrane and nucleus normal,tissues interspace normal.While in pure injury group,there were hemorrhage and edema in the spinal cord and vacuolation in cells,dissolve and abolition in nerve fibers.After treatment,the spinal cord in 0.25MPa HBO groups and 0.25 MPa HBO+hormone(L,M) groups recovered most significant.The edema and vacuolation relieved,form of nerve cells reversed,the structure array being integritly.Conclusion: Treating with HBO can decrease the mortality,and can prevent or relieve the pathological changes of SCI,recover the function of spinal cord.