2012•Zhongguo yaolixue tongbaoRequires access
Protein S-nitrosylation and neurodegenerative diseases
Nai‐Hong Chen
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Abstract
S-nitrosylation is the reversible redox modification of nitric oxide(NO) acting on the protein's cysteine residues,which is an important way that NO plays a role in vivo.Recent studies have shown that it participates in a variety of physiological and pathological processes,especially the S-nitrosylation of some target proteins has been proven to be involved in neurodegenerative diseases,which is summarized in this paper.