New process in the synthesis of diethylene glycol monoallyl ether

Without the introduction of other solvents,the synthesis of diethylene glycol monoallyl ether[2-(2-allyloxy-ethoxy)-ethanol] was prepared with diethylene glycol,allyl chloride and sodium hydroxide as the raw material and tetrabutylammonium chloride as phase transfer catalyst by the method of Williamson. The product was characterized by IR and 1H NMR spectra. The effects of reaction time,reaction temperature,molar ratio,the amount of alkali and catalyst on the yield of target product were investigated. The optimal condition was determined as follows:n(diethylene glycol)∶n(sodium hydroxide)∶n(allyl chloride) =6∶1.2∶1,m(catalyst)∶m(allyl chloride)=0.05∶1,at 80℃for 3h. The yield of the product could reach 86.7% and the purity was 99.2% under the optimal reaction condition.