Clinical Application of Lung Recruitment Maneuvers in the Treatment of Acute Respiratory Distress Syndrome

【Objective】To investigate the effect and risk of lung recruitment maneuvers(RM) in treating acute respiratory distress syndrome(ARDS).【Methods】 ARDS patients were randomly divided into the control group and the treatment group.In addition to conventional treatment,the control group received mechanical ventilation by using lung protective ventilation strategy of applying small tidal volume via PB760 respiratory machine and optimal positive end-expiratory pressure(PEEP).In addition to the same treatment as the control group,the treatment group further received RM.Oxygen indexes(PaO2/FiO2) before applying RM and at 12h,24h,72h after applying RM were measured.The rate of carbon dioxide elimination(PaCO2) in arterial blood and the appearance of ventilator-associated lung injury were compared and analyzed.【Results】In comparison to the control group,the treatment group significantly improved in oxygen indexes(PaO2/FiO2) at 12h,24h,and 72h after applying RM(P0.05),and the level of PaO2 also significantly lowered(P0.05).No significant difference was found between the two groups in the occurrence rate of ventilator-associated lung injury.【Conclusion】The employment of small tidal volume and optimal PEEP in conjunction with lung recruitment maneuvers(RM) to treat ARDS is both safe and effective.