2010•World Clinical DrugsRequires access

Progress on cancer gene therapy by adeno-associated virus vector

Anqi Li

Abstract

Gene therapy may become one of the effective approaches for cancer.Vectors used to carry foreign genes play an important role in cancer gene therapy.Among the currently developed virus vectors,the adeno-associated virus (AAV) vector is of many advantages,such as safety,expression in long-term and wide host range.It has been widely used in gene therapy.This review describes the basic biology of AAV,recent progress on AAV vector and AAV-mediated therapeutic vectors for cancer gene therapy.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Adeno-associated virus, Genetic enhancement, Vector (molecular biology), Medicine, Viral vector, Vectors in gene therapy, Gene, Cancer