2012The Journal of Medical Theory and PracticeRequires access

Clinical Effect of Fentanyl Combined with Ropivacaine for Cesarean Section Postoperative Epidural Analgesia

Feng Chaona

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Abstract

Objective:To compare analgesic effect and side effects of morphine with different concentrations of fentanyl both composite ropivacaine for cesarean section epidural analgesia.Methods:120 ASA Ⅰ ~Ⅱ parturient women undergoing cesarean section received PCEA for 48 hours after operation,randomly divided into control group(M group),the observation group(Group F1,F2,F3 group).The PCEA solution contained of 0.178 8% ropivacaine plus morphine 0.1mg/ml,or fentanyl(3μg/ml,4μg/ml and 5μg/ml).Fixed analgesia pump infusion rate of 2ml/h,at different time follow-up to assess the VAS score of rest pain,dynamic pain,modified Bromage score and side effects.Results:The F3 and the M group have satisfactory analgesic effect,but the side effects of M group was significantly higher than other groups(P0.05).Conclusion:5μg/ml fentanyl plus 0.178 8% ropivacaine for epidural analgesia have exact effect with low incidences of side effects,which is worthy of clinical promotion.

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Objective:To compare analgesic effect and side effects of morphine with different concentrations of fentanyl both composite ropivacaine for cesarean section epidural analgesia.Methods:120 ASA Ⅰ ~Ⅱ parturient women undergoing cesarean section received PCEA for 48 hours after operation,randomly divided into control group(M group),the observation group(Group F1,F2,F3 group).The PCEA solution contained of 0.178 8% ropivacaine plus morphine 0.1mg/ml,or fentanyl(3μg/ml,4μg/ml and 5μg/ml).Fixed analgesia pump infusion rate of 2ml/h,at different time follow-up to assess the VAS score of rest pain,dynamic pain,modified Bromage score and side effects.Results:The F3 and the M group have satisfactory analgesic effect,but the side effects of M group was significantly higher than other groups(P0.05).Conclusion:5μg/ml fentanyl plus 0.178 8% ropivacaine for epidural analgesia have exact effect with low incidences of side effects,which is worthy of clinical promotion.

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Available abstract

Objective:To compare analgesic effect and side effects of morphine with different concentrations of fentanyl both composite ropivacaine for cesarean section epidural analgesia.Methods:120 ASA Ⅰ ~Ⅱ parturient women undergoing cesarean section received PCEA for 48 hours after operation,randomly divided into control group(M group),the observation group(Group F1,F2,F3 group).The PCEA solution contained of 0.178 8% ropivacaine plus morphine 0.1mg/ml,or fentanyl(3μg/ml,4μg/ml and 5μg/ml).Fixed analgesia pump infusion rate of 2ml/h,at different time follow-up to assess the VAS score of rest pain,dynamic pain,modified Bromage score and side effects.Results:The F3 and the M group have satisfactory analgesic effect,but the side effects of M group was significantly higher than other groups(P0.05).Conclusion:5μg/ml fentanyl plus 0.178 8% ropivacaine for epidural analgesia have exact effect with low incidences of side effects,which is worthy of clinical promotion.

Key concepts: Medicine, Ropivacaine, Fentanyl, Anesthesia, Morphine, Analgesic, Side effect (computer science), Surgery

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